KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KA4
All Species:
19.7
Human Site:
S87
Identified Species:
28.89
UniProt:
O75676
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75676
NP_001006945.1
772
85606
S87
E
H
T
R
T
E
R
S
V
L
E
L
V
R
Q
Chimpanzee
Pan troglodytes
XP_508900
901
98668
S214
E
H
T
R
T
E
R
S
V
L
E
L
V
R
Q
Rhesus Macaque
Macaca mulatta
XP_001114877
772
85557
S87
E
H
T
R
T
E
R
S
V
L
E
L
V
R
Q
Dog
Lupus familis
XP_854926
772
85603
S87
E
H
T
R
T
E
R
S
V
L
E
L
V
R
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z2B9
773
85721
S87
E
H
T
R
T
E
R
S
V
L
E
L
V
R
Q
Rat
Rattus norvegicus
Q63531
735
82865
R113
R
V
R
T
K
M
E
R
D
I
L
A
D
V
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506738
716
80894
A81
Y
I
G
E
I
V
L
A
L
E
H
L
H
K
L
Chicken
Gallus gallus
Q5F3L1
789
89022
Q93
E
H
T
R
T
E
R
Q
V
L
E
H
I
R
Q
Frog
Xenopus laevis
P10665
733
82620
R113
R
V
R
T
K
M
E
R
D
I
L
A
D
V
H
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
R118
R
V
R
T
K
M
E
R
D
I
L
V
E
V
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
V315
E
H
T
K
T
E
R
V
V
L
E
A
I
Q
R
Honey Bee
Apis mellifera
XP_395099
910
102507
Q118
E
H
T
K
T
E
R
Q
V
L
E
A
V
R
D
Nematode Worm
Caenorhab. elegans
Q18846
772
87050
I97
Q
T
D
T
K
L
H
I
V
M
E
Y
V
R
G
Sea Urchin
Strong. purpuratus
XP_786494
918
102561
D92
S
K
L
N
L
I
L
D
Y
V
N
G
G
E
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
Baker's Yeast
Sacchar. cerevisiae
P18961
677
76646
S72
E
T
L
P
S
S
L
S
S
P
K
L
R
N
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.4
98.6
96.7
N.A.
95.8
41.3
N.A.
56
64
41
41.9
N.A.
27
45.1
48.1
48.2
Protein Similarity:
100
85.6
98.9
98
N.A.
96.7
60.6
N.A.
71.6
78.4
59
60.3
N.A.
38.9
60.1
64.3
61.8
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
6.6
80
0
0
N.A.
60
73.3
26.6
0
P-Site Similarity:
100
100
100
100
N.A.
100
6.6
N.A.
26.6
86.6
6.6
13.3
N.A.
86.6
80
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.4
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
35.6
37.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
7
0
0
0
25
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
7
19
0
0
0
13
0
13
% D
% Glu:
57
0
0
7
0
50
19
0
0
7
57
0
7
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
0
0
0
0
0
0
0
0
7
7
0
7
% G
% His:
0
50
0
0
0
0
7
0
0
0
7
7
7
0
7
% H
% Ile:
0
7
0
0
7
7
0
7
0
19
0
0
13
0
0
% I
% Lys:
0
7
0
13
25
0
0
0
0
0
7
0
0
7
0
% K
% Leu:
0
0
13
0
7
7
19
0
7
50
19
44
0
0
13
% L
% Met:
0
0
0
0
0
19
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
0
0
0
0
7
0
0
7
13
% N
% Pro:
0
0
0
7
0
0
0
0
0
7
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
13
0
0
0
0
0
7
38
% Q
% Arg:
19
0
19
38
0
0
50
19
0
0
0
0
7
50
7
% R
% Ser:
7
0
0
0
7
7
0
38
7
0
0
0
0
0
0
% S
% Thr:
0
13
50
25
50
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
19
0
0
0
7
0
7
57
7
0
7
44
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
7
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _